We are interested in developing and applying computational tools for biological problems. Our Structural Bioinformatics work is oriented to prediction and analysis of protein structure and its relationship to protein function. Areas of interest include:

  • Protein Sequence to Protein Structure

    • comparative (homology) modeling
    • sequence-to-structure alignments
    • structure evaluation
model-template comparison
  • Protein Structure to Protein Function

    • identification and characterization of ligand binding sites
    • modeling of protein-ligand complex structures
    • description of ligand binding selectivity
    • identification of biologically active forms
    • prediction of the functional effect of mutations

  • Biological Systems of interest

    • protein domains involved in chromatin remodeling (bromodomain, chromodomain, etc.)
    • genetic metabolic diseases

Contact:

Roberto Sanchez
Department of Structural and Chemical Biology
Mount Sinai School of Medicine
Box 1677, 1425 Madison Avenue, New York, NY 10029
roberto.sanchez @ mssm.edu




Icahn (East) Building, 16th floor.
Office: Room 16-20, Lab: Room 16-34A

PHONE:  Office +1 (212) 659 8648, Lab +1 (212) 659 5505/5477
FAX:  +1 (212) 659 8232
URL: http://www.sanchezlab.org

Joining the lab: MSSM PhD and MD/PhD programs. For other positions contact Roberto Sanchez at the address above.